Natural Compound Formula RM88 Significantly Reduces Blood Alcohol Concentration in Humans

Blood alcohol concentration and psychomotor effects.

This study assessed the effect of intravenous alcohol infusions on psychomotor impairment and compared it with that of alcohol administered orally. Comparisons were made between three European drink-driving limits of blood alcohol concentration (BAC) (20, 50 and 80 mg 100 ml-1) and an oral dose of alcohol 0.75 mg kg-1. Twelve volunteers, aged 22-34 yr, were recruited. At targets of 20, 50 and a...

Back calculation of blood alcohol concentration.

Medicolegal Alcohol Determination - Blood- or Breath-Alcohol Concentration?

Measuring the concentration of alcohol in body fluids represents a large part of the workload at forensic science and toxicology laboratories. In traffic-law enforcement, breath-alcohol testing is used worldwide for roadside screening and for evidential purposes. Many jurisdictions have adopted per se laws which make it a crime to drive with a blood- or breath-alcohol concentration above a pres...

Blood-brain transfer of Pittsburgh compound B in humans

In the labeled form, the Pittsburgh compound B (2-(4'-{N-methyl-[(11)C]}methyl-aminophenyl)-6-hydroxy-benzothiazole, [(11)C]PiB), is used as a biomarker for positron emission tomography (PET) of brain β-amyloid deposition in Alzheimer's disease (AD). The permeability of [(11)C]PiB in the blood-brain barrier is held to be high but the permeability-surface area product and extraction fractions in...

Mibefradil reduces blood glucose concentration in db/db mice

OBJECTIVE Numerous recent studies suggest that abnormal intracellular calcium concentration ([Ca2+]i) is a common defect in diabetic animal models and patients. Abnormal calcium handling is an important mechanism in the defective pancreatic β-cell function in type 2 diabetes. T-type Ca2+ channel antagonists lower blood glucose in type 2 diabetes, but the mechanism remains unknown. METHODS We ...